Efficient DNA sequencing methods
نویسنده
چکیده
make it much easier to obtain information on the amino acid sequence of proteins than on their structures or functions. The sequences of homologous proteins can diverge greatly over time, even though the structure or function of the proteins change little.Thus,much can be inferred about an uncharacterized protein when significant sequence similarity is detected with a wellstudied protein.This has been a key motivation for the comparison of DNA and protein sequences.Other goals of sequence comparison include phylogenetic reconstruction and the detection of genes and regulatory regions (see the article by David Haussler on pp. 12–15).
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تاریخ انتشار 1999